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The PIONEER program tested oral semaglutide the first GLP-1 receptor agonist available as a pill rather than injection. Across multiple PIONEER trials in T2DM, oral semaglutide produced HbA1c and weight reductions
Efficacy, safety and cardiovascular outcomes of oncedaily oral semaglutide in patients with type 2 diabetes: The PIONEER programme - Thethi - 2020 - Diabetes, Obesity and Metabolism - Wiley Online Library
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