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Only a few week old (2026 jan 22) systematic review revealed that GLP-1 agonists have the greatest benefit for younger non-diabetic female patients. https://diabetesjournals.org/care/article/48/2/292/157724/Efficacy -of-GLP-1-Receptor-Agonists-on-Weight ...

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I-M-150847, a novel GLP-1 and GIP receptor dual agonist, reduces body weight gain and improves glycemic control in the rodent model of type 2 diabetes and obesity | bioRxiv

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